Rangers had ruled out cyanide poisoning or poaching because the animals were found with their tusks intact.
“I have a report which said there was a bacterial infection,” parks and wildlife authority spokesman Tinashe Farawo told AFP.
The dead animals were young elephants between two and six years old.
Farawo said the calves were too short to reach treetop leaves and may have ingested the bacteria by grazing on infected plants.
Zimbabwe counts more than 84,000 elephants — almost double the southern African country’s ecological carrying capacity of between 45,000 and 50,000.
Hwange, which sprawls over 14,600 square kilometres (5,600 square miles), has a normal maximum capacity of 15,000 elephants but currently holds between 45,000 and 53,000.
Scores of its pachyderms have succumbed to starvation and lack of water in recent years as a result.
Others have been poisoned by poachers for their ivory, used to make ornaments and traditional medicine in Asia and the Middle East.
At least 300 elephants died of cyanide poisoning at water holes in Hwange in 2013.
Neighbouring Botswana, home to the world’s largest elephant population of around 130,00, lost around 300 elephants early this year. They are thought to have succumbed to natural toxins.